Sulfated polysaccharides of brown seaweeds - ligands of toll-like receptors
نویسندگان
چکیده
منابع مشابه
microRNAs are ligands of Toll-like receptors.
It has long been known that microRNAs (miRNAs) can regulate target gene expression at the post-transcriptional level. Recent studies, however, have revealed that miRNAs can also be transported from donor cells to recipient cells, in which these RNAs function in a novel manner as ligands of Toll-like receptors. Here, we review the latest findings on these unconventional miRNAs, with special emph...
متن کاملAntioxidant Activity of Sulfated Seaweeds Polysaccharides by Novel Assisted Extraction
Seaweeds have an extremely numerous of species in the world and been able to be divided into several developmental systems. Broadly, three types of seaweeds can be defined according to their color: brown seaweeds, green seaweeds, and red seaweeds. Thousands of years ago, mankind used seaweeds as food and medicine. Seaweed extracts are gaining increasing attention due to their unique composition...
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Atherosclerosis is a disease characterized by inflammation in the arterial wall. Atherogenesis is dependent on the innate immune response involving activation of Toll-like receptors (TLRs) and the expression of inflammatory proteins. TLRs, which recognize various pathogen-associated molecular patterns, are expressed in various cell types within the atherosclerotic plaque. Microbial agents are a...
متن کاملToll-Like receptors (TLRs) and their ligands.
The innate immune system is an evolutionally conserved host defense mechanism against pathogens. Innate immune responses are initiated by pattern recognition receptors (PRRs), which recognize microbial components that are essential for the survival of the microorganism. PRRs are germline-encoded, nonclonal, and expressed constitutively in the host. Different PRRs react with specific ligands and...
متن کاملSulfated polysaccharides fucoidans from brown algae
The immunotropic activity of structurally different fucoidans and their derivatives towards isolated immune blood cells, effectors of innate immune system, was studied. The most potent effect was observed for high molecular weight fucoidan CF from the alga Chordaria flagelliformis, whose backbone is built of (1→3)-linked units of α-L-fucopyranose, and branches included residues of α-D-glucuroni...
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ژورنال
عنوان ژورنال: Biomeditsinskaya Khimiya
سال: 2012
ISSN: 2310-6905,2310-6972
DOI: 10.18097/pbmc20125803318